Do you have expertise in, and passion for, testing inhalation products and conducting routine testing in support of early phase drug product stability studies? Would you like to apply your expertise to impact our Research Associate III role in Durham, NC in a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca might be the one for you!

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

In 2013, AstraZeneca acquired Pearl to expand and strengthen its respiratory products portfolio, We have made strides in bringing therapies to asthma patients. Our mission and vision are to develop differentiated therapeutics for widely prevalent respiratory disease conditions, including chronic obstructive pulmonary disease (COPD), by utilizing a proprietary drug delivery platform and existing therapeutic agents administered in metered-dose inhalers (MDIs). Join us as Research Associate IIi at our Durham, NC site, which is situated in Research Triangle Park; the leading center of innovation in the Southeast! We are dedicated to creating a culture of inclusion and teamwork.

Be welcomed into our inclusive network of diverse and high-performing teams. Have the support, trust, and respect to thrive here – fair leadership, great workplaces, and energized teams who always have each other’s back. For those with a shared drive and passion for impacting people’s lives, experience a sense of belonging like no other.

What you will do:

As a Research Associate III, you will support IPD DPI and MDI product development from product definition stages to product approval and launch by devising and conducting analytical experiments.

• Under general guidance, design experiments and conduct analytical experimental work related to advancing IPD product quality and performance.

• Able to identify aberrant data and effectively communicate observations to project management. Communicate project status and concerns to management.

• Under general guidance, execute stability-indicating analytical methods to support pMDI and DPI development of inhaled biologics drug product platforms using HPLC, UHPLC, and CE, in combination with various specialized detection schemes such as UV-Vis, FLD, MALS, and DLS

• Conduct routine testing in support of early phase drug product stability studies using bioanalytical methods: SEC, IEC, CE (R/NR), cIEF, CZE, HIC, Potency, and A280 content assays.

• Effectively document experiments and results in appropriate formats.

• Execute specialized bioanalytical sample handling and preparation techniques required for stability-indicating analytical methods

• Under general guidance, prepare technical reports and/or CoAs to summarize data and document experimental conclusions, evaluate data for trends indicative of product performance, method performance, or analyst performance.

Education:

• University degree (BS or MS) in the field of chemistry, pharmaceutical science, or related field.

Required:

• MS with 0+ years, BS with a minimum of six years of pharmaceutical industry experience.

• Minimum of four years' experience testing inhalation products preferred, especially DPIs, with a variety of active pharmaceutical ingredients at different stages of development.

• In-depth knowledge in at least one relevant field: HPLC, GC, KF moisture testing, aerosol performance testing.

• Familiarity with relevant ICH, USP, EP, and FDA guidance documents as well as cGXPs in support of inhaled drug product testing.

• Must be able to effectively communicate verbally and through technical writing (documentation of laboratory experiments).

Why AstraZeneca?

At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth, and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Where can I find out more?

• Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

• Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

• Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

• About Operations: https://www.youtube.com/watch?v=gak5Ham8oUw

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.