PURPOSE OF THE ROLE

Principle Scientist with expertise in in vivo pharmacology in oncology and immune-oncology, will provide scientific leadership and expertise to support multiple immune-oncology projects. The candidate must be competent to lead cross-functional discovery project team. He/she should have demonstrated scientific leadership and expertise in the field of oncology and cancer immunotherapy. The person should actively strengthen the cancer immunotherapy pipeline through championing internal projects and managing/supporting collaborations with external partners.

Expectations:

• Work in collaboration with other team members in designing immune-oncology models to test new immumodulators/bispecific antibodies in murine and other animal model systems
• Be responsible to build up in vivo pharmacology team
• Analyzes complex issues, significantly improves, changes or adapts existing methods and techniques.
• Develops research solutions that require extensive analysis and detailed investigation.
• Collaborate effectively with other colleagues across the global organization, as well as manage external collaborations with various industry partners
• Present scientific results to multidisciplinary teams and senior management
• Develops new ideas, concepts and approaches for immunotherapy and project workflow
• Keeps on the look-out, develops, and incorporates when needed new assay technologies or platforms to expedite the research and improve data quality, reliability, and predictive value when moving to later stages of early clinical development
• Qualifications and Skills:

• Familiar with animal facility management and daily maintenance.

• Ability to conceptualize new ideas for immunotherapy and research assay tools
• Excellent interpersonal skills with the ability to interact effectively with people, internally and externally
• Team oriented work ethic and ability to work in cross-functional teams
• Outstanding presentation and interpersonal communication skills
• Ability to demonstrate effectiveness and growth in a fast-paced and dynamic team environment
• PhD or Master degree in a relevant scientific field (e.g. immunology, cancer immunology, oncology), with more than 3 years of experience in an industrial setting
• A strong background with in vivo platform set up for evaluating IO related molecules, including but not limited to CDX, PDX, syngenic model, humanized mice model, PBMC engraft model et al. Be Familiar with these tumor models and mechanisms of anti-tumor responses with strength in the analysis of the activity of human innate and adaptive cell populations and measuring anti-tumor effector lymphocyte responses

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