Are you looking for an opportunity in high-speed pharmaceutical manufacturing where you can use your technical background to drive continuous improvement and work on the installation of new equipment and processes to meet future demands?  Are you passionate about making a huge impact as a Manufacturing Engineer (Packaging) in a company that follows science and turns ideas into life-changing medicines? If so, then this position is for you!

AstraZeneca is at an exciting time of new products and launches. We get to work with innovative and scientific products on our leading-edge end to end supply chain, using the latest technologies and modern facilities

In Operations, we have a big ambition – to deliver more medicines to patients, quicker and more affordably. Backed by the investment, leadership, and a clear plan to get there, we bring personal dedication and out-of-the-box thinking.

Join the team where everyone feels a personal connection to the people that we impact. From our science labs to manufacturing at scale, we are committed to delivering at the highest quality. It’s inspiring and rewarding work, influencing every part of the product lifecycle to deliver life-changing medicines. To ultimately make people’s lives better – from patients and their families to all of us in society.

Our West Chester Supply Site is a very dynamic and growing manufacturing site within the AstraZeneca Global Operations network and is located just north of Cincinnati, Ohio. In addition to serving as the global COVID vaccine production site for AstraZeneca, the West Chester site encompasses Bulk API Microsphere manufacturing, Aseptic Pharmaceutical Formulation, multi-line Isolator/Barrier Vial and Syringe Filling, and specialty Packaging Operations for Vials and Auto-Injectors that supports growing franchises in Diabetes, Respiratory, and Vaccines. Our site is one of 30 production facilities in 18 countries with over 700 people collaborating to connect powerful medications to patients in more than 60 countries around the world. We focus on providing a collaborative environment where everyone feels comfortable and able to be themselves. Being able to bring your full self to work every day is at the core of AstraZeneca’s priorities. On-site amenities include a Health and Wellness clinic, as well as a Cafeteria Grille serving breakfast and lunch items for employees and guests. We also have a Great Place to Work Counsel, involving committees of employees who coordinate several activities related to community outreach, sustainability, health and wellness, and social events

Mon-Fri (Day-Shift Role)

The Manufacturing Engineer is responsible for ensuring one technical process exists within the PET/Facility. This includes equipment, materials, process, and procedures with applicable validation. Leads improvement initiatives as the technical expert and acts as the first line of support for all project-related work. Responsible for maintaining a strong relationship with Technical Operations and Quality areas, as well as, collaborating within the PET/Facility and with other PET Engineers. Serves as the single point of contact for all technical issues.

What you'll do:

• Ensures there is one technical process with centerlines, critical process parameters, material fit for use, and operating procedures are clear and delivers a capable process.

• Leads the following continuous process improvement efforts: changeover reduction, yield improvements, OEE improvements, maintenance reliability and waste reduction for improvement of automated pharmaceutical manufacturing equipment.

• Ensures success criteria for technology transfer and validation are clear and the process is capable for the merge into the PET/Facility process.

• Generates a variety of URS, FAT, SAT, commissioning, and IQ/OQ/PQ protocols/ reports.

• Coordinate and support PET’s/Facility improvement initiatives that define equipment data, equipment capabilities, utilization, efficiencies, and obsolescence. Manages the life-cycle of assets.

• Maintain external technical relationships and collaborates with equipment and material suppliers.

• Identify, develop, generate and manage the implementation of appropriate change controls to improve processes and address root causes identified in investigations.

• Perform and maintain risk management activities for new and existing processes/equipment.

• Initiate deviations and performs/facilitates the technical investigations and assessment of impacts.

Essentials:

Education:

• BS degree required in Engineering, or related science.

Required:

• Training or experience in the applicable following technologies: mechanics, hydraulics, pneumatics, vacuum technology, electronics, programmable logic controllers, HMI, Historian/reporting, computerized systems, vision systems, refrigeration, test equipment for electrical and mechanical trouble-shooting, aseptic/controlled environment, unit operations, formulation, packaging, process validation, cleaning validation, technology transfer, change control, applied statistics.

• Proficiency in at least one of the following subject areas: automation/ controls, aseptic/packaging equipment, process/materials, maintenance, validation.

Desired:

• Strong verbal and written communication skills.

• Consistent record to work effectively in a team environment.

• Ability to generate and interpret technical documents.

• Experience managing external technical relationships.

• Strong mechanical/technical capability.

Why AstraZeneca

At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.

So, what’s next

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

Find out more on Social Media:

• LinkedIn https://www.linkedin.com/company/1603/

• Facebook https://www.facebook.com/astrazenecacareers/

• Instagram https://www.instagram.com/astrazeneca/?hl=en

• About Operations https://www.youtube.com/watch?v=gak5Ham8oUw

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.