Position: Director of Immunology

Department: Discovery

Report to: CEO

Location: Taicang

About Connect Biopharmaceuticals

Connect Biopharmaceuticals is a China-based global clinical-stage company focused on discovery and development of novel immune modulators for the treatment of autoimmune diseases and inflammation.

Responsibilities

? Leading and championing immunology projects from discovery to early clinical development.

? Developing and executing efficient strategies for target identification, prioritization and validation; review, propose, initiate, and implement new pre-clinical therapeutic antibody drug discovery and development programs in the field of Immunology and Inflammation.

? Building, coaching and managing a team of in-house scientists.

? Collaborating with MNC, CRO and academic partners; employ cutting-edge in vitro and in vivo animal and human models to advance drug discovery and development programs up to and including IND filing.

? Collaborating with clinical and business teams to support clinical studies. Leading project team meetings, and presenting updates to senior management.

? Facilitating and/or coaching team member for the writing of patents and regulatory documents. Presenting non-proprietary results on scientific conferences and publish in peer reviewed journals.

Job requirements:

? PhD in immunology or related discipline;

? 5 to 10 plus years of industrial experience, ideally in the field of immunology.

? Experience of leading a drug discovery project in biopharmaceutical companies;

? Demonstrated track record of independent critical thinking and scientific achievement in research, exemplified by strong publications in leading journals;

? Experience in immunology, as well as molecular and cellular biology;

? Experience or knowledge of in vivo models of immunology and inflammatory diseases;

? Understanding of fundamentals and practice of antibody discovery, engineering, and development;

? Excellent English and Chinese communication skills, as well as people organizational skill

? Enthusiasm in laboratory experimentation

职位: 免疫学总监

部门:

汇报上级: 总裁

工作地点: 太仓

公司简介

康乃德生物医药是立足于中国的，具有全球权益临床阶段产品的新药创新公司。康乃德专注于发现和开发新型免疫调节制剂，治疗自身免疫性疾病和炎症。

职责描述

?领导和支持从发现到早期临床开发的免疫学项目；

?制定和执行有效的目标识别，优先排序和验证策略; 审查，提出，启动和实施免疫学和炎症领域的新的临床前治疗性抗体药物发现和开发计划；

?建立，指导和管理内部科学家团队；

?与跨国公司，CRO和学术合作伙伴合作; 采用先进的体外和体内动物和人体模型，推进药物发现和开发计划，包括IND申请；

?与临床和业务团队合作，支持临床研究。领导项目团队会议，并向高级管理层汇报最新情况；

?促进和/或指导团队成员撰写专利和注册文件。在科学会议上报告非专利成果，在专业期刊上发表文章。

任职要求：

?免疫学或相关学科博士;

?5至10年以上的工业经验，最好是在免疫学领域；

?在生物制药公司领导药物发现项目的经验；

?以在国际主要专业期刊上发表的文章，展示出在研究中独立的批判性思维和科学成就记录;

?在免疫学以及分子和细胞生物学方面的经验;

?免疫和炎症性疾病体内模型的经验或知识;

?了解抗体发现，工程和开发的基本原理和实践;

?优秀的英语和中文沟通技巧，以及人员组织能力；

?对实验室实验充满热情

上班地址：靠近上海嘉定区

苏州康乃德生物医药公司(简称“苏州康乃德”)由具有制药行业新药开发及国内外创业成功经验的海归博士团队于2012年初创建成立，公司毗邻上海的(苏州)太仓市生物医药产业园。
苏州康乃德专注于以G蛋白偶联受体(简称“GPCR”)为靶点开发相关治疗自身免疫及肿瘤基本的创新药物，公司具有自主开发的GPCR单克隆抗体药物技术，并致力成为GPCR单克隆抗体药物开发方面独特的国际领先企业。我们将深入拓展该技术平台并开发出系列相关抗体药物，同时也通过积极引进具有全球专利开发权益的技术和产品，利用日益完善的生物医药研发外包CRO服务，快速推进各个新药开发项目的临床前研究并申报获得美国FDA和中国SFDA临床研究(IND)批文、继而自主或与大型制药企业完成进一步产业化开发及实现最终的市场推广。
苏州康乃德拥有若干相关药物开发技术及产品专利的全球使用权，并已向美国专利局申报了自主开发的GPCR单克隆抗体技术全球专利一项。目前苏州康乃德在积极推进开展美国Arena制药公司新药项目的临床前开发和产业化工作，所开发的药物将用于治疗过敏性鼻炎和过敏性皮炎。

公司地址：
215400 中国，江苏省，太仓市，北京西路6号，研发东楼3楼
邮箱：swlu@connectpharm.com
公司网站：http://www.connectbiopharm.com/