Title: Principal scientist

Field: Monoclonal antibody generation

Job description：

1. Work independently or lead a team to conduct monoclonal antibody generation by hybridoma, single B- cell cloning, immune library or other methods required for a specific therapeutic program.

2. Participate or take a lead in establishing a comprehensive technology platform, acquire and initiate now antibody technologies, improve and refine existing technologies.

3. May need to lead and establish the high throughput mAb screening platform with protein based and cell based assays, and the compatible functional assays.

4. Perform data analysis and data summary; prepare progress report and present the data to upper manager or collaborator in Chinese or English.

5. This position will also be responsible for maintaining/generating documents and records on daily basis, coordinate laboratory tasks across the company and perform additional duties as assigned.

Qualifications：

1. PhD or equivalent with >5 years experience with major or training in biology or biochemistry field, MS/BS in biology background with > 10 years relevant experience.

2. Extensive experience in one or more of the following technologies including transgenic animal platform, hybridoma, B-cell cloning, phage/yeast display, etc.

3. Extensive experience in high throughput screening assays such as ELISA, FACS, Acumen/Mirraball, iQue, HTRF, etc. Extensive knowledge or experience in biologics functional is a plus.

4. Mammalian cell culture experience and skills are highly desired.

6. Strong capability of team work and handling multi-tasks, good communication skills in both Chinese and/or English and ability of coordinating activities cross functional groups. Grant or patent application experience is a big plus.

7. Trained in notebook recording, data analysis and report preparation.

Others：

1. Good organizational and planning skills in order to meet deadlines and to handle multi tasks.

2. Strong aspiration for drug discovery work, diligent, self-motivated, independent, strong sense of responsibility.

3. Be able to record and present results in both Chinese and English.

4. Good interpersonal skills for building relationships across functions internally and externally. Effective collaboration with colleagues and partners.

Title: Scientist or Senior scientist

Field: Monoclonal antibody generation

Job description：

1. Work independently or in a team to conduct monoclonal antibody generation by hybridoma, B- cell cloning, immune library or other methods required for a specific therapeutic program.

2. Perform cell fusion and hybridoma development, single B-cell cloning or phage display immune library generation, antibody screening by protein based or cell based binding assay, or protein or cell based functional assays.

3. Perform data analysis and data summary; prepare progress report and present the data to upper manager or project leaders.

4. This position will also be responsible for maintaining/generating documents and records on daily basis, coordinate common laboratory tasks and perform additional duties as assigned.

Qualifications：

1. PhD with 0-2 years experience and major or training in biology or biochemistry field, MS/BS in biology background with > 2 years relevant experience.

2. Experienced or familiar with one or more of the following technologies including transgenic animal platform, hybridoma, B-cell cloning, phage/yeast display, etc.

3. Experienced or familiar with high throughput screening assays such as ELISA, FACS, Acumen/Mirraball, iQue, HTRF, etc.

4. Mammalian cell culture experience and skills are highly desired.

5. Strong capability of team work and handling multi-tasks, good communication skills and ability of coordinating activities cross functional groups.

6. Trained in notebook recording, data analysis and report preparation.

Others：

1. Good organizational and planning skills in order to meet deadlines and to handle multi tasks.

2. Strong aspiration for drug discovery work, diligent, self-motivated, independent, strong sense of responsibility.

3. Be able to record and present results in both Chinese and English.

4. Good interpersonal skills for building relationships across functions internally and externally. Effective collaboration with colleagues and partners.

Title: Associate scientist or scientist

Field: Animal immunization and screening

Job description：

1. Work independently or in a team to prepare the immunogens and immunize wild type or fully human antibody transgenic mice for antibody generation by hybridoma and B-cell cloning technologies.

2. Need to receive and QC test the antigens and immunogens, immunize the animals and test bleed according to the schedules. Prepare antiserum and check the immune response by specified assays such as ELISA, western blot, FACS, receptor binding assay, etc.

3. Schedule the immunization and bleeding activities of multiple discovery projects, organize and coordinate project activities from different project team. Provide summary to the supervisor and project leaders.

4. This position will also be responsible for maintaining/generating documents and records on daily basis, coordinate common laboratory tasks and perform additional duties as assigned.

Qualifications：

1. MS/BS in biology background with 0-5 years relevant experience in animal handling and/or immunization.

2. Experienced or familiar with animal handling, animal welfare, animal immunization and test bleeding, antiserum preparation.

3. Experienced or familiar with one or more of the assays including ELISA, FACS, SDS-PAGE, Western blot, etc.

5. Strong capability of team work and handling multi-tasks, good communication skills and ability of coordinating activities cross functional group.

6. Trained in notebook recording, data analysis and report preparation.

上班地址：生物纳米科技园SIP BioBay

和铂医药是一家专注于肿瘤免疫领域创新药物研究与开发的全球化运营生物医药公司。公司将运用其拥有的全部自主知识产权的全人源单抗的转基因鼠系列核心技术平台，建立下一代治疗性肿瘤抗体药物产品管线,并将围绕Harbour的两大平台拓展合作与授权业务。公司总部及研发基地位于中国上海，另外在美国马塞诸塞州剑桥设立商业运营中心，在荷兰鹿特丹设立抗体研发平台创新中心，在波士顿地区设立了创新中心包括实验室和研发团队，也将在江苏昆山设立研发基地。公司拥有资深管理团队以及丰富的药物研究与开发经验。和铂医药要为满足中国及全球病人的需求而不断努力，依托拥有自主知识产权的核心技术平台,创建一个在肿瘤治疗领域有科学与技术领导力的国际性生物医药公司。同时, 在药物研发领域建立以技术平台为基础的对外合作，整合新的技术，推动中国整个抗体研发产业的进步。

Company Overview
Harbour BioMed is a global biotechnology company discovering and developing innovative therapeutics for cancer with a focus on immuno-oncology and autoimmunity/inflammation. The company's discovery and development programs are centered around its two patented transgenic mouse platforms for human antibody discovery.
The company is building its proprietary pipeline internally, through collaborations with co-development partners, as well as through selective preclinical and clinical stage asset acquisitions. Harbour BioMed also licenses the platforms to companies and academic institutions through its Harbour Antibodies subsidiary.
Harbour BioMed has headquarters and an R&D site in Shanghai, business operations in Cambridge, MA, and antibody platform development in Rotterdam, The Netherlands.
The company has an innovation center including research lab and a development team in Boston. Also, we are expanding to Kunshan site in Jiangsu for our R&D operation.