主要职责

• 研究小分子抗生素化合物的作用机理。
• 用系统生物学和各类组学的方法确立药物靶点并进行验证。
• 开发可用于药物筛选的分子与生化反应体系，特别是细菌基因的转录翻译过程, 和细菌的细胞壁合成与能量代谢途径。
• 开发实验动物细菌感染模型用于靶点和小分子药物的研究。

任职要求

• 已取得分子生物化学，微生物遗传，医学微生物，动物兽医或相关生物科学硕士或博士学位，具有0-6年相关经历。
• 具有研究细菌传染病和实验动物模型的科研经历，和有优良的数据分析能力的申请人会被优先考虑。
• 具备良好的团队合作精神，优秀的协作能力和英文沟通能力。
• 应聘者必须具备严谨的科研素养，并能严格对实验记录和电子文档进行归档整理。

Key Responsibilities

• Perform determination of the mode of action of antibacterial small molecules.

• Responsible for target identification, using systems biology techniques involving transcriptomics, proteomics and metabolomics.

• Develop novel biochemical assays for analysis of multi-component systems such as transcription, translation, respiration and cell membrane/wall biosynthesis.

• Develop animal infection models for target validation or efficacy testing.

Minimum Requirements

• Master or PhD degree in molecular biology, biochemistry, microbial genetics, physiology or the related biological sciences with 0-6 year experience.

• Knowledge and experience in bacterial infections is highly appreciated. Demonstrable skills in data analysis including programming and statistics would be a plus.

• Good team player, excellent collaboration and communication skills
• Scientific integrity is a must; candidate should be professional in maintaining lab notebooks and electronic files.

Salary

Negotiation

上班地址：北京市海淀区永泰庄北路1号